The Global Mice Model Services Market was valued at USD 1,978 Million in 2023 and is projected to reach USD 3,698.11 Million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 7.2% during the forecast period (2024-2032). This growth trajectory reflects the expanding role of murine models in drug discovery, disease research, and personalized medicine development across academic and pharmaceutical sectors.
As biomedical research progresses toward more complex disease modeling and targeted therapies, the demand for sophisticated mouse models continues to accelerate. In this analysis, we profile the Top 10 Companies in the Mice Model Services Industry—the pioneers delivering cutting-edge genetic models and preclinical research solutions that drive therapeutic breakthroughs.
🔟 1. Charles River Laboratories
Headquarters: Wilmington, Massachusetts, USA
Key Offering: Custom models, CRISPRevolution genome editing, Research Models & Services
Charles River leads the market with 25,000+ research models globally. They offer comprehensive solutions including immunodeficient mice, humanized models, and genetically engineered strains supporting oncology, immunology, and CNS research.
Innovation Highlights:
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Industry-leading CRISPR/Cas9 genome editing platform
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FDA-recommended IND-enabling studies
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Six strategic acquisitions expanding CNS capabilities since 2020
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9️⃣ 2. The Jackson Laboratory
Headquarters: Bar Harbor, Maine, USA
Key Offering: JAX® Mice, Phenotyping, Custom model generation
This non-profit research institution maintains the world’s most extensive catalog of genetically defined mice, distributing over 12,000 strains annually to 30,000+ researchers globally.
Innovation Highlights:
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Industry-standard NSG® immunodeficient models
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15,000+ mutant mouse strains in repository
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Expanding humanized immune system platforms
8️⃣ 3. Taconic Biosciences
Headquarters: Rensselaer, New York, USA
Key Offering: GEMs, Humanized models, Microbiome solutions
Taconic specializes in genetically engineered mouse models (GEMs) serving 15 of the top 20 global pharma companies, with vertical integration from model design through preclinical studies.
Innovation Highlights:
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Proprietary TruAB™ human antibody platform
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Exclusive licensor of key IP-protected models
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Leading germ-free mouse model expertise
7️⃣ 4. Envigo
Headquarters: Indianapolis, Indiana, USA
Key Offering: Outbred stocks, Custom breeding, Research models
Envigo delivers research models to 100+ countries, with core strengths in consistent outbred stocks and specialized diet formulations for metabolic disease research.
Innovation Highlights:
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Global standard Sprague-Dawley rat strains
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High-capacity custom model development
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Diet-induced disease model specialists
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6️⃣ 5. Crown Biosciences
Headquarters: Taicang, China
Key Offering: PDX models, In vivo pharmacology, Translational platforms
Crown maintains the largest commercial PDX collection globally with 5,000+ models across multiple cancer types, enabling highly predictive oncology research.
Innovation Highlights:
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HuBase™ – Most diverse PDX collection
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Early commercializer of immunocompetent humanized models
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Imageable PDX models for treatment monitoring
5️⃣ 6. GenOway
Headquarters: Lyon, France
Key Offering: Custom GMO models, Ready-to-use models
This French biotech pioneer standardizes complex genetically modified model development through proprietary gene editing technologies.
Innovation Highlights:
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SYNTap™ rapid model generation system
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Patent-protected immuno-oncology models
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CRISPR-mediated conditional knock-in tech
4️⃣ 7. PsychoGenics
Headquarters: Paramus, New Jersey, USA
Key Offering: Neurobehavioral models, CNS drug discovery
Specializing in central nervous system research, PsychoGenics combines proprietary models with AI-driven behavioral analysis.
Innovation Highlights:
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SmartCube® AI behavioral phenotyping
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Industry-standard ASD/schizophrenia models
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High-throughput CNS screening
3️⃣ 8. Pharmaron
Headquarters: Beijing, China
Key Offering: Disease models, Efficacy testing, Toxicology
Pharmaron has emerged as China’s leading preclinical CRO with extensive capabilities in localized disease model development.
Innovation Highlights:
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Market-leading hepatic disease models
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Comprehensive infectious disease solutions
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GMP-compliant preclinical facilities
2️⃣ 9. Horizon Discovery Group
Headquarters: Cambridge, United Kingdom
Key Offering: Gene editing, X-MAN® models, CRISPR screening
Now part of PerkinElmer, Horizon provides validated genetically engineered models and advanced gene editing services.
Innovation Highlights:
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Pioneering X-MAN® gene mutant models
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60+ patents in gene editing IP portfolio
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CRISPR screening services
1️⃣ 10. Shanghai Model Organisms Center (Shanghai SLAC)
Headquarters: Shanghai, China
Key Offering: Custom models, Gene editing, Phenotypic analysis
China’s largest commercial mouse model provider serves the booming APAC biopharma market with localized development services.
Innovation Highlights:
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Leading humanized immune system models
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Specialized NASH model portfolio
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One of Asia’s largest SPF facilities
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🔬 Outlook: The Future of Mice Model Services
The mice model services sector is transforming through convergence of advanced genetic engineering, digital technologies, and translational research needs. Key developments shaping market evolution:
📈 Key Market Trends:
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Humanization wave: Growing demand for models with human biological systems for better therapeutic predictability
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CRISPR revolution: Genome editing driving faster, more precise model development at reduced costs
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Therapeutic specialization: Expanding portfolios for oncology, neurology, and metabolic diseases
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Digital transformation: AI-powered phenotyping and imaging analysis integration
The companies profiled represent the vanguard of preclinical innovation, positioned to capitalize on these trends through continued investment in next-generation model development and research services.
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