The Global Natural Angelica Extract Ligustilide Market was valued at USD 843 million in 2023 and is projected to reach USD 1.26 billion by 2032, growing at a Compound Annual Growth Rate (CAGR) of 4.6% during the forecast period (2024-2032). This expansion is driven by increasing adoption in traditional Chinese medicine, rising demand for natural cosmetic ingredients, and growing clinical research validating ligustilide’s neuroprotective and anti-inflammatory benefits.
As pharmaceutical and nutraceutical applications for Angelica extracts expand, manufacturers are investing in advanced extraction technologies and global standardization. This analysis examines the Top 10 Natural Angelica Extract Ligustilide Suppliers—pioneers in phytochemical production, research-grade materials, and GMP-certified active ingredients.
🔟 1. BOC Sciences
Headquarters: Shirley, New York, USA
Core Product: 98% HPLC-grade Ligustilide Reference Standards
BOC Sciences maintains ISO-certified facilities for high-purity phytochemical production, supplying analytical standards to research institutions and pharmaceutical developers worldwide. Their ligustilide products support pharmacological studies and quality control applications.
Technical Advantages:
- GC/MS and NMR-validated purity documentation
- Stability-tested reference materials
- Custom isolation and characterization services
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9️⃣ 2. NUONA TECHNOLOGY
Headquarters: Xi’an, China
Core Product: Angelica Sinensis Extract (95-98% Ligustilide)
This Shaanxi-based manufacturer specializes in supercritical CO₂ extraction of Traditional Chinese Medicine compounds, supplying bulk botanical ingredients to Asian nutraceutical formulators.
Technical Advantages:
- Vertically integrated supply chain from cultivation
- Patented low-temperature extraction process
- Annual production capacity exceeding 50 metric tons
8️⃣ 3. TAUTO BIOTECH
Headquarters: Shanghai, China
Core Product: Customized Angelica Extract Blends (10-50% Ligustilide)
TAUTO combines GMP manufacturing with TCM expertise, offering standardized extracts for global supplement and personal care markets. Their facility holds multiple international certifications for herbal production.
Technical Advantages:
- FDA-registered API manufacturing
- Stability studies supporting 36-month shelf life
- Halal and Kosher certification options
7️⃣ 4. Pharmaffiliates
Headquarters: Mohali, India
Core Product: USP-grade Ligustilide Analytical Standards
Specializing in phytochemical reference materials, Pharmaffiliates serves quality control laboratories with fully characterized Angelica extract compounds, complete with method validation protocols.
Technical Advantages:
- Pharmacopeia-compliant certification
- Batch-specific impurity profiles
- GMP analytical testing services
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6️⃣ 5. ChemScence
Headquarters: Nanjing, China
Core Product: 98%+ Ligustilide for Formulation Development
ChemScence provides cGMP-grade Angelica compounds to pharmaceutical development teams, with comprehensive analytical documentation for regulatory submissions.
Technical Advantages:
- ICH stability testing protocols
- Residual solvent monitoring to USP standards
- Custom particle size optimization
5️⃣ 6. ApexBio Technology
Headquarters: Houston, Texas, USA
Core Product: Research-grade Ligustilide
ApexBio supplies bioactive plant compounds to academic and industrial researchers, supporting drug discovery programs investigating ligustilide’s pharmacological mechanisms.
Technical Advantages:
- Cell-based activity validation data
- Metabolomics profiling available
- Global logistics network
4️⃣ 7. EXTRASYNTHESE
Headquarters: Lyon, France
Core Product: Cosmetic-grade Angelica Extracts
This European supplier specializes in plant-derived actives for beauty formulations, offering ligustilide-rich extracts with documented skin benefits.
Technical Advantages:
- ISO 22716 cosmetic manufacturing
- Organic and Ecocert compliant options
- Clinical dermal tolerance studies
3️⃣ 8. Cayman Chemical
Headquarters: Ann Arbor, Michigan, USA
Core Product: Ligustilide Biomarkers
Cayman provides analytically certified reference materials for pharmacokinetic studies and herbal product authentication.
Technical Advantages:
- Stable isotope-labeled standards available
- Metabolite profiling services
- FDA GLP-compliant documentation
2️⃣ 9. Hairui Chemical
Headquarters: Zhengzhou, China
Core Product: Industrial-scale Angelica Extracts
Hairui supplies cost-effective botanical ingredients to manufacturers, with batch-to-batch consistency for large-scale production needs.
Technical Advantages:
- 500+ ton annual extraction capacity
- Custom concentration blending
- Competitive bulk pricing
1️⃣ 10. Shanghai Tauto Biotech
Headquarters: Shanghai, China
Core Product: Pharmaceutical-grade Ligustilide API
Specializing in Traditional Chinese Medicine APIs, Tauto Biotech produces GMP-certified Angelica compounds for licensed herbal medicines worldwide.
Technical Advantages:
- EDQM CEP certification
- FDA Drug Master File availability
- Process validation support
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🌍 Market Outlook: Accelerating Research Expands Applications
The natural ligustilide sector is transitioning from traditional remedies to evidence-based medicine, with clinical studies revealing broad therapeutic potential. Pharmaceutical and cosmetic innovators are driving demand for standardized, clinically-validated extracts.
📈 Growth Catalysts:
- FDA approvals for botanical drug applications featuring Angelica extracts
- Cosmetic industry shift toward bioactive natural ingredients
- Increasing R&D investment in neuroprotective phytochemicals
- Standardization of TCM extracts for global regulatory compliance
Get Full Report Here: Natural Angelica Extract Ligustilide Market – View in Detailed Research Report
These market leaders demonstrate how traditional plant medicine meets modern scientific validation, creating new opportunities in global healthcare and personal care markets through standardized, quality-controlled Angelica extracts.