The Global Solvent Degassing Systems Market was valued at USD 185 million in 2023 and is projected to reach USD 263.31 million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 4.00% during the forecast period (2023-2032). This steady expansion stems from escalating HPLC adoption, tightening pharmaceutical quality controls, and automated laboratory workflows across key markets in North America, Europe, and Asia-Pacific regions.
With analytical precision becoming non-negotiable in chromatography applications, solvent degassing systems have transitioned from optional accessories to essential components. These systems eliminate dissolved gases that distort analytical results through four primary technologies: vacuum, ultrasonic, membrane, and heating methods. Below we analyze the Top 10 Companies in the Solvent Degassing Systems Industry – established manufacturers and emerging specialists driving innovation across laboratory and industrial applications.
🔟 1. Knauer Wissenschaftliche Geräte GmbH
Headquarters: Berlin, Germany
Key Offering: AZURA Membrane Degassers
This German precision engineering firm leads in HPLC degassing technology with its patented AZURA series, achieving oxygen removal below 0.1 ppm – critical baseline stability for sensitive LC-MS applications. Knauer serves pharmaceutical quality control labs across 60+ countries.
Technology Advantages:
- Gas-selective PTFE membranes with 10,000-hour lifespan
- Simultaneous 4-channel operation at 10 mL/min flow rates
- Plug-and-play integration with major LC systems
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9️⃣ 2. Agilent Technologies
Headquarters: Santa Clara, California, USA
Key Offering: InfinityLab Degassers
Agilent’s micro-volume degassers employ proprietary Direct Flow Technology, maintaining <0.1 psi ripple pressure – the industry benchmark for UHPLC systems. Their vacuum membrane systems serve 80% of top-20 pharma companies.
Technology Advantages:
- 10,000 psi operating pressure rating
- 50% smaller footprint than previous generations
- Automated self-diagnostics
8️⃣ 3. Shimadzu Corporation
Headquarters: Kyoto, Japan
Key Offering: DGU-20A5 Vacuum Degassers
Shimadzu’s 5-channel degassers feature real-time pressure monitoring and automated vacuum regulation – preferred by Asian pharmaceutical manufacturers for stability in continuous QC operations.
Technology Advantages:
- 16-stage vacuum precision control
- 30% faster gas removal than industry average
- IoT-enabled performance tracking
7️⃣ 4. IDEX Health & Science
Headquarters: Lake Forest, Illinois, USA
Key Offering: DEGASi® Modular Systems
IDEX dominates the OEM degasser market, supplying modular units to analytical instrument manufacturers. Their configurable platforms support 1-6 channels with flow rates up to 15 mL/min per channel.
Technology Advantages:
- Patented turbulence-free flow paths
- Quick-change membrane cartridges
- Explosion-proof industrial models
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Solvent Degassing Systems Market – View in Detailed Research Report
6️⃣ 5. Phenomenex, Inc.
Headquarters: Torrance, California, USA
Key Offering: Degasser NU Cartridges
Phenomenex revolutionized maintenance with disposable degasser cartridges, reducing downtime in academic and contract research labs. Their systems maintain 95% gas removal efficiency for 6-12 months of continuous use.
Technology Advantages:
- Tool-free cartridge replacement in <2 minutes
- 50% cost savings versus conventional systems
- Compatible with all major LC brands
5️⃣ 6. The Chemours Company
Headquarters: Wilmington, Delaware, USA
Key Offering: Nafion™ Membrane Systems
Chemours’ Nafion polymer technology delivers simultaneous solvent dehydration and degassing – critical for moisture-sensitive applications in semiconductor and battery research.
Technology Advantages:
- Removes water to <50 ppm while degassing
- Chemical resistance to aggressive solvents
- Zero consumables or moving parts
4️⃣ 7. Welch Materials
Headquarters: Cockeysville, Maryland, USA
Key Offering: Vacuum Degassing Stations
Welch’s industrial-scale systems process up to 150 mL/min for high-throughput labs. Their FDA-compliant models dominate North American pharmaceutical manufacturing.
Technology Advantages:
- 21 CFR Part 11 compliant software
- Batch process automation
- 50-100L reservoir capacities
3️⃣ 8. ULFA Tech
Headquarters: Seoul, South Korea
Key Offering: Ultrasonic Degassing Chambers
This Korean innovator’s 40kHz ultrasonic systems remove microbubbles in industrial coatings and inks. Their technology gained rapid adoption in display manufacturing across East Asia.
Technology Advantages:
- 500L tank capacity models
- 60% energy reduction versus nitrogen sparging
- Continuous flow operation
2️⃣ 9. Flom Corporation
Headquarters: Tokyo, Japan
Key Offering: Space-Saving Degassing Pumps
Flom’s compact units combine vacuum pumps with membrane modules, achieving 90% dissolved gas removal in under 5 minutes – ideal for space-constrained Japanese and Chinese labs.
Technology Advantages:
- 300 mL/min solvent processing
- Only 35dB operational noise
- 50% smaller than conventional systems
1️⃣ 10. DEGASi Global
Headquarters: Networked global facilities
Key Offering: Multi-Vendor System Integration
This solutions provider architects customized degassing workflows by combining best-in-class technologies from leading manufacturers, serving multinational laboratories.
Value Proposition:
- Single-source regulatory compliance
- Hybrid technology configurations
- Global service network
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Solvent Degassing Systems Market – View in Detailed Research Report
🔬 Market Outlook: Automation and Precision Driving Evolution
The solvent degassing market is undergoing a transformation as laboratories prioritize data integrity under tightening regulations like USP ⟨665⟩ and ICH Q2(R1). Emerging trends reflect the industry’s dual focus on precision and workflow efficiency.
📈 Key Development Vectors:
- Pharma sector dominance: 60% of demand stems from HPLC applications in drug development
- Sustainability shift: Helium-free systems gaining traction amid supply chain concerns
- Smart integration: 30% of new systems now interface with LIMS platforms
- Hybrid solutions: Combining vacuum/membrane/ultrasonic technologies for challenging solvents
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Solvent Degassing Systems Market – View in Detailed Research Report
As analytical requirements grow more stringent across industries, these innovators continue advancing degassing technologies that are becoming indispensable for research, quality control, and manufacturing processes worldwide.