The Global Human and Porcine Fibrin Sealant Market was valued at USD 122 million in 2024 and is projected to reach USD 166.27 million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 3.50% during the forecast period (2024-2032). This growth is driven by increasing surgical procedures, technological advancements in hemostatic products, and expanding applications in trauma and cardiovascular surgeries worldwide.
As healthcare providers prioritize improved patient outcomes and reduced hospital stays, fibrin sealants have become critical tools in modern surgical practice. This analysis examines the Top 10 Companies in the Human and Porcine Fibrin Sealant Industry – the biomedical innovators developing breakthrough solutions for surgical bleeding control.
🔟 1. Baxter International Inc.
Headquarters: Deerfield, Illinois, USA
Key Products: TISSEEL, ARTISS
Baxter dominates the fibrin sealant market with its FDA-approved products TISSEEL and ARTISS. The company’s formulations are widely used in cardiovascular, orthopedic, and general surgeries across North America and Europe.
Clinical Advantages:
- Proven reduction in surgical bleed times by 50-60%
- Available in both spray and drip application formats
- Validated for use in over 25 surgical specialties
Download FREE Sample Report: Human and Porcine Fibrin Sealant Market – View in Detailed Research Report
9️⃣ 2. Johnson & Johnson (Ethicon)
Headquarters: New Brunswick, New Jersey, USA
Key Products: EVICEL, SURGIFLO
J&J’s Ethicon division offers EVICEL, the first aprotinin-free fibrin sealant approved by the FDA. The company has established strong clinical evidence across 15+ surgical applications.
Clinical Advantages:
- Reduced risk of allergic reactions compared to bovine-derived products
- Proprietary delivery system for precise application
8️⃣ 3. Shanghai RAAS Blood Products Co., Ltd.
Headquarters: Shanghai, China
Key Products: Fibrin Sealant Kit (Human)
As China’s largest plasma product manufacturer, Shanghai RAAS commands over 40% of the domestic fibrin sealant market. The company benefits from China’s rapidly growing medical device sector.
Clinical Advantages:
- Cost-effective alternative to imported products
- Approved for use in 9 surgical specialties by NMPA
7️⃣ 4. Hualan Biological Engineering Inc.
Headquarters: Xinxiang, China
Key Products: Fibrin Sealant (Human)
Hualan Biological has become a key supplier to Chinese hospitals seeking domestically produced hemostatic products. The company maintains rigorous plasma screening protocols.
Clinical Advantages:
- Specialized formulations for hepatic surgeries
- ISO 13485 certified manufacturing facilities
Download FREE Sample Report: Human and Porcine Fibrin Sealant Market – View in Detailed Research Report
6️⃣ 5. BIOSEAL BIOTECH
Headquarters: Beijing, China
Key Products: Porcine Fibrin Sealant
BIOSEAL specializes in porcine-derived fibrin sealants, providing an alternative for markets with restrictions on human blood products. Their technology has gained acceptance across Middle Eastern hospitals.
Clinical Advantages:
- Advanced viral inactivation processes
- Compatible with Islamic medical guidelines
5️⃣ 6. CSL Behring
Headquarters: King of Prussia, Pennsylvania, USA
Key Products: RiaSTAP, Fibrogammin
CSL Behring applies its expertise in plasma protein therapies to specialized fibrin sealants for rare bleeding disorders. The company supplies products to over 70 countries.
Clinical Advantages:
- High-purity fibrinogen concentrations
- Indicated for congenital fibrinogen deficiency
4️⃣ 7. Harbin Hanbang Medical
Headquarters: Harbin, China
Key Products: Fibrin Sealant (Human)
This Chinese biotechnology firm has developed specialized fibrin sealant formulations approved for trauma surgeries. The company focuses on cost-effective solutions for public hospitals.
Clinical Advantages:
- Rapid clot formation (under 60 seconds)
- Included in Chinese national reimbursement lists
3️⃣ 8. Shanghai Songli Biotechnology
Headquarters: Shanghai, China
Key Products: Fibrin Sealant Kit
Songli Biotechnology innovates in combination products that integrate fibrin sealants with collagen matrices. Their products target complex surgical cases requiring enhanced hemostasis.
Clinical Advantages:
- Reduced rebleeding rates in clinical trials
- Patented stabilization technology
2️⃣ 9. Zhejiang Sealant Pharma
Headquarters: Hangzhou, China
Key Products: Fibrin Sealant (Porcine)
Zhejiang Sealant has developed dual-purpose fibrin sealants suitable for both human and veterinary applications. The company is expanding into Southeast Asian markets.
Clinical Advantages:
- Stable at room temperature for 24 months
- Cost 30-40% lower than Western alternatives
1️⃣ 10. TissuGlu Surgical Adhesive
Headquarters: Munich, Germany
Key Products: TissuGlu (Porcine-derived)
This European innovator specializes in plastic surgery adhesives that complement traditional fibrin sealants. Their products are particularly effective in abdominoplasty procedures.
Clinical Advantages:
- Reduces seroma formation by 70%
- Patent-protected application system
Get Full Report Here: Human and Porcine Fibrin Sealant Market – View in Detailed Research Report
🏥 Surgical Innovation: The Future of Fibrin Sealants
The fibrin sealant market continues to evolve with new formulations addressing unmet clinical needs. While human-derived products maintain majority share, porcine alternatives are gaining acceptance in specific regions.
📈 Market-Shaping Developments:
- Expanding indications in minimally invasive procedures
- Integration with robotic surgical systems
- Development of antimicrobial fibrin matrices
- Growing adoption in ambulatory surgical centers
The companies profiled represent the cutting edge of surgical hemostasis, driving innovations that improve patient outcomes across multiple medical specialties.
Get Full Report Here: Human and Porcine Fibrin Sealant Market – View in Detailed Research Report